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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WIPF2
All Species:
21.82
Human Site:
T212
Identified Species:
48
UniProt:
Q8TF74
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TF74
NP_573571.1
440
46289
T212
R
E
K
P
L
P
P
T
P
G
Q
R
L
H
P
Chimpanzee
Pan troglodytes
XP_511807
182
19950
Rhesus Macaque
Macaca mulatta
XP_001088658
104
10714
Dog
Lupus familis
XP_850217
440
46420
T212
R
E
K
P
L
P
P
T
P
G
Q
R
L
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6PEV3
440
46279
T212
R
E
K
P
L
P
P
T
P
G
Q
R
L
H
P
Rat
Rattus norvegicus
Q6IN36
487
49732
T242
P
R
P
P
L
P
P
T
P
S
R
A
L
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517787
163
16570
Chicken
Gallus gallus
XP_001235113
473
48338
T209
R
E
K
P
L
P
P
T
P
G
Q
R
A
P
A
Frog
Xenopus laevis
NP_001079978
426
44520
T209
R
E
K
P
L
P
P
T
P
G
H
R
A
P
A
Zebra Danio
Brachydanio rerio
NP_001002165
441
45246
T209
R
E
K
P
L
P
P
T
P
E
Q
R
G
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37370
817
82575
P235
L
P
T
H
V
S
N
P
P
Q
A
P
P
P
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.1
23.6
97.2
N.A.
93.8
39.8
N.A.
24.3
59.2
69.3
69.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
41.3
23.6
98.1
N.A.
96.8
49.2
N.A.
27.9
64.9
77.2
76.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
100
N.A.
100
46.6
N.A.
0
80
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
0
100
N.A.
100
53.3
N.A.
0
80
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
31.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
10
19
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% D
% Glu:
0
55
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
46
0
0
10
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
10
0
0
28
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
55
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
64
0
0
0
0
0
0
0
37
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
10
64
0
64
64
10
73
0
0
10
10
37
37
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
46
0
0
0
0
% Q
% Arg:
55
10
0
0
0
0
0
0
0
0
10
55
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% S
% Thr:
0
0
10
0
0
0
0
64
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _